Solution:

About the DI "Any Change Interrupt" of ADAM-5051, there're few mistake in the User's Manual (page 252). Set Inputs Any Change Interrupt Request 600+NI, 22, 06, 60, CC, FF Where CC : range 01-40H, the 2-character hexadecimal start DI channel number of the ADAM-5000/CAN. FF : means the DI channel. Bit 0 means 1st channel of CC Bit 1 means 2nd channel of CC Bit 2 means 3rd channel of CC Bit 3 means 4th channel of CC Bit 4 means 5th channel of CC Bit 5 means 6th channel of CC Bit 6 means 7th channel of CC Bit 7 means 8th channel of CC So, following information just for your reference. Assume that the ID of ADAM-5000/CAN is 01H. Only one ADAM-5051 be used on slot 0. Baudrate is 20Kbps. ; Set Inputs Any Change Interrupt Request 601 22 06 60 01 01 581 60 06 60 01 Change the status of channel 0 (DI0) of ADAM-5051, then follow message will response automatically. 581 4f 20 60 01 01 581 4f 20 60 01 00 581 4f 20 60 01 01 581 4f 20 60 01 00 581 4f 20 60 01 01 . . . . .